The list of leading wicket-takers on this ground is dominated by pacers. However, a spinner tops the chart. Mohammad Rafique from Bangladesh has claimed the most wickets at Chepauk. He has eight wickets to his name in three matches at an average of 21.50. He also has a four-wicket haul on the ground. He picked up four wickets for 65 runs against Africa XI while playing for Asia XI in 2007. Ajit Agarkar, a former Indian speedster, is in second place with seven wickets in three matches at an average of 4.15. Ajit also took four wickets against England here. He picked up four wickets for 34 runs in 2002. Former South African pacer Morne Morkel is in third place with seven wickets. He has picked up seven wickets in three matches at an average of 21.5. Below is the list of bowlers who have taken the most wickets at this venue.
|
Player | Span | Matches | Innings | Overs | Maidens | Wickets | BBI | Average | Econ | SR |
| Mohammad Rafique (Bangladesh) | 1998-2007 | 3 | 3 | 30 | 0 | 8 | Apr-65 | 21.5 | 5.73 | 22.5 |
| Ajit Agarkar (India) | 2002-2007 | 3 | 2 | 19 | 1 | 7 | Apr-34 | 11.28 | 4.15 | 16.2 |
| Morne Morkel (South Africa) | 2007-2011 | 3 | 3 | 27 | 1 | 7 | Mar-50 | 16.28 | 4.22 | 23.1 |
| Harbhajan Singh (India) | 2002-2015 | 5 | 4 | 39 | 2 | 7 | Mar-48 | 23.85 | 4.28 | 33.4 |
| Simon O’Donnell (Australia) | 1987-1989 | 3 | 3 | 24.4 | 2 | 6 | Apr-39 | 15 | 3.64 | 24.6 |
| Bhuvneshwar Kumar (India) | 2012-2017 | 3 | 3 | 23 | 3 | 6 | Mar-68 | 20 | 5.21 | 23 |
| Andre Russell (West Indies) | 2011-2011 | 3 | 3 | 23.1 | 1 | 6 | Apr-49 | 21 | 5.43 | 23.1 |
| Ravi Rampaul (West Indies) | 2011-2011 | 1 | 1 | 10 | 0 | 5 | May-51 | 10.2 | 5.1 | 12 |
| Aaqib Javed (Pakistan) | 1997-1997 | 1 | 1 | 10 | 0 | 5 | May-61 | 12.2 | 6.1 | 12 |
| Craig McDermott (Australia) | 1987-1987 | 2 | 2 | 17 | 1 | 5 | Apr-56 | 13.8 | 4.05 | 20.4 |
