Peter Aho from Nigeria holds the record for best bowling figures in T20Is, claiming six wickets for five runs against Sierra Leone in 2021. India pacer Deepak Chahar is at number two, picking up six wickets for seven runs against Bangladesh in 2019. Uganda bowler Dinesh Nakrani holds the third position, taking six wickets for seven runs against Lesotho in 2021. Check out the list of bowlers with the best bowling figures in a T20I innings.
| Player | Overs | Mdns | Runs | Wkts | Econ | Team | Opposition | Match Date |
| Peter Aho | 3.4 | 1 | 5 | 6 | 1.36 | Nigeria | v Sierra Leone | 24-Oct-21 |
| Deepak Chahar | 3.2 | 0 | 7 | 6 | 2.1 | India | v Bangladesh | 10-Nov-19 |
| Dinesh Nakrani | 4 | 1 | 7 | 6 | 1.75 | Uganda | v Lesotho | 19-Oct-21 |
| Ajantha Mendis | 4 | 2 | 8 | 6 | 2 | Sri Lanka | v Zimbabwe | 18-Sep-12 |
| JJ Smit | 4 | 1 | 10 | 6 | 2.5 | Namibia | v Uganda | 10-Apr-22 |
| Ajantha Mendis | 4 | 1 | 16 | 6 | 4 | Sri Lanka | v Australia | 8-Aug-11 |
| Obed McCoy | 4 | 1 | 17 | 6 | 4.25 | West Indies | v India | 1-Aug-22 |
| Peter Langat | 4 | 1 | 17 | 6 | 4.25 | Kenya | v Mali | 20-Nov-22 |
| Hernan Fennell | 4 | 0 | 18 | 6 | 4.5 | Argentina | v Panama | 10-Nov-21 |
| Jan Frylinck | 4 | 0 | 24 | 6 | 6 | Namibia | v U.A.E. | 5-Oct-21 |
